化学标识

Sofosbuvir IP Impurity D / Fluorouridine / Sofosbuvir Desphosphate Impurity

CAS 863329-66-2 · C10H13FN2O5

01化学标识

Lazychem IDLC-28291
CAS RN863329-66-2
PubChem CID11311503
Molecular formulaC10H13FN2O5
Molecular weight260.22 g/mol
IUPAC name1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKeyARKKGZQTGXJVKW-VPCXQMTMSA-N

02结构与立体化学

2D structurePubChem CID 11311503
Two-dimensional chemical structure of Sofosbuvir IP Impurity D / Fluorouridine / Sofosbuvir Desphosphate Impurity, CAS 863329-66-2
Two-dimensional structure for the PubChem identity linked to this record. Confirm the identifiers before analytical use.

The parsed structure contains 2 rings, includes aromatic atoms, includes aliphatic carbon, has 4 defined stereocentres, contains at least one halogen atom. These statements are calculated from the published structure string.

Defined stereocentres4
Ring count2
Secondary amines0
Tertiary amines0
SMILESC[C@]1([C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)CO)O)F
InChI未列出

03Stereochemistry

The published structure contains 4 defined and 0 unassigned tetrahedral stereocentres. The exact wedge and dash depiction is shown above.

Defined centres4Structure assigned
Unassigned centres0Structure unspecified
Assignment statusFully assignedExact published identity
Tetrahedral upper bound≤ 16Before symmetry reduction

Published same-connectivity configurations

4 records

These records have the same connectivity, molecular formula and protonation layer, but a different complete InChIKey stereochemical layer. Only separately structure-linked records are shown.

Scope: The mathematical 2^n value is only an upper bound. Symmetry and other stereogenic elements can change the number of distinct stereoisomers. A hypothetical configuration is not published as a compound record without a verified structure identity.

04印度监管状态

Exact-compound status is evaluated only against the published name and CAS number. Confirm the current official instrument before a regulatory decision.

05名称与关联

原料药与母体药物

Sofosbuvir

杂质与相关化合物

名称与关联

  • Sofosbuvir IP Impurity D
  • Fluorouridine / Sofosbuvir Desphosphate Impurity
  • (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine
  • 863329-66-2
  • PSI-6206
  • Uridine, 2'-deoxy-2'-fluoro-2'-methyl-, (2'R)-
  • Ro-2433
  • GS-331007
  • 1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyl-tetrahydrofuran-2-yl)pyrimidine-2,4-dione
  • 44V7045CXS
  • RefChem:418387
  • 2'-Deoxy-2'-fluoro-2'-C-methyluridine

杂质与相关化合物

06来源