API e farmaco progenitore

Aprepitant

CAS 170729-80-3 · C23H21F7N4O3 · 24 Impurezze e composti correlati

01API e farmaco progenitore

2D structurePubChem CID 135413536
Two-dimensional chemical structure of Aprepitant, CAS 170729-80-3
Two-dimensional structure for the PubChem identity linked to this record. Confirm the identifiers before analytical use.
CAS RN170729-80-3
PubChem CID135413536
Molecular formulaC23H21F7N4O3
IUPAC name3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,4-dihydro-1,2,4-triazol-5-one
Defined stereocentres3
Unassigned stereocentres0

02Screening strutturale delle nitrosammine

N-nitrosoNot detected
Secondary amine0
Tertiary N-methyl amine0

Structure-only screen. Manufacturing conditions, nitrite sources, pH, temperature and purge controls require a separate process assessment.

03Stato in India

Exact-compound comparison only. Confirm the current official instrument before making a regulatory decision.

05Fonti