API et médicament parent
Macitentan
CAS 441798-33-0 · C19H20Br2N6O4S · 25 Impuretés et composés apparentés
01API et médicament parent
Structure 2DPubChem CID 16004692
| CAS RN | 441798-33-0 |
|---|---|
| PubChem CID | 16004692 |
| Formule moléculaire | C19H20Br2N6O4S |
| Nom IUPAC | 5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(propylsulfamoyl)pyrimidin-4-amine |
| Stéréocentres définis | 0 |
| Stéréocentres non attribués | 0 |
02Dépistage structural des nitrosamines
Ce résultat n’établit ni formation ni absence de risque. Une évaluation propre au procédé est nécessaire.
03Statut en Inde
Seul le composé exact est comparé aux identifiants publiés. Vérifiez l’instrument officiel en vigueur avant toute décision réglementaire.
04Impuretés et composés apparentés
Structure 2DPubChem CID 63868414
2-((5-Bromopyrimidin-2-yl)oxy)ethan-1-ol
1246922-88-2
Structure 2DPubChem CID 68724716
![Structure 2D: 2-[[6-Amino-5-(4-bromophenyl)-4-pyrimidinyl]oxy]-ethanol, CAS 2211059-05-9](/structures/pubchem/68724716/2211059-05-9-2-6-amino-5-4-bromophenyl-4-pyrimidinyl-oxy-ethanol-2d-structure-300.png)
Structure 2DPubChem CID 129011924
![Structure 2D: 2-[5-(4-Bromophenyl)-6-(propylsulfamoylamino)pyrimidin-4-yl]oxyacetic acid, CAS 1433875-14-9](/structures/pubchem/129011924/1433875-14-9-2-5-4-bromophenyl-6-propylsulfamoylamino-pyrimidin-4-yl-oxyacetic-acid-2d-structure-300.png)
Structure 2DPubChem CID 19735262
5-(4-Bromophenyl)-4,6-dichloropyrimidine
146533-41-7
Structure 2DPubChem CID 132276185
Structure 2DPubChem CID 163562345
5-(4-bromophenyl)-6-ethoxy-N-(propylsulfamoyl)pyrimidin-4-amine
FSHCKXVVXGGMGM-UHFFFAOYSA-N
Structure 2DPubChem CID 54191439
5-(4-Bromophenyl)pyrimidine-4,6-diol
706811-25-8
Structure 2DPubChem CID 606665
5-Bromo-2-chloropyrimidine
32779-36-5
Structure 2DPubChem CID 78358426
5-desbromo-5-Chloro Macitentan
2443747-63-3
Structure 2DPubChem CID 137250148
6-Amino-5-(4-bromophenyl)-4(3H)-pyrimidinone
2211054-46-3
Structure 2DPubChem CID 137157140
Hydroxy Macitentan
2365406-85-3
Structure 2DPubChem CID 10196441
Macitentan IMpurity
556796-88-4
Structure 2DPubChem CID 67041378
Macitentan Impurity A
1433875-21-8
Structure 2DPubChem CID 21041267
Structure 2DPubChem CID 132278565
Macitentan Impurity B
2211054-90-7
Structure 2DPubChem CID 21041324
Structure 2DPubChem CID 142312698
Macitentan Impurity D
2089065-77-8
Structure 2DPubChem CID 177847861
Macitentan Pyrimidine N-Nitroso N-Propyl Impurity
ILQFSPIKZBDHGZ-UHFFFAOYSA-N
Structure 2DPubChem CID 168429883
![Structure 2D: N-[5-(4-Bromophenyl)-6-[2-(2-pyrimidinyloxy)ethoxy]-4-pyrimidinyl]-N'-propyl-sulfamide, CAS 2211059-00-4](/structures/pubchem/168429883/2211059-00-4-n-5-4-bromophenyl-6-2-2-pyrimidinyloxy-ethoxy-4-pyrimidinyl-n-propyl-sulfamide-2d-structure-300.png)
Structure 2DPubChem CID 70813943
![Structure 2D: N-[5-(4-Bromophenyl)-6-[2-hydroxyethoxy]-4-pyrimidinyl]-N'-propylsulfamide, CAS 1393813-43-8](/structures/pubchem/70813943/1393813-43-8-n-5-4-bromophenyl-6-2-hydroxyethoxy-4-pyrimidinyl-n-propylsulfamide-2d-structure-300.png)
Structure 2DPubChem CID 71500858
![Structure 2D: N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-propylsulfamide, CAS 1393813-42-7](/structures/pubchem/71500858/1393813-42-7-n-5-4-bromophenyl-6-chloro-4-pyrimidinyl-n-propylsulfamide-2d-structure-300.png)
Structure 2DPubChem CID 25099191
N-Despropyl Macitentan
1103522-45-7
Structure 2DPubChem CID 71462322
N-Despropyl-N-ethyl Macitentan
441796-13-0
Structure 2DPubChem CID 176476622
N-Nitroso Macitentan Dimer Impurity
GHQOUCLLRNZSPT-UHFFFAOYSA-N
Structure 2DPubChem CID 71500857
tert-butyl N-(propylsulfamoyl)carbamate
1393813-40-5
05Sources
- S01