Chemical identity

Vincristine Sulfate EP Impurity G / Formylleurosine (Free Base)

CAS 54022-49-0 · C46H54N4O10

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-30834
PubChem CID76972843
NameVincristine Sulfate EP Impurity G / Formylleurosine (Free Base)
CAS RN54022-49-0
Molecular formulaC46H54N4O10
Molecular weight822.94 g/mol
IUPAC nameMethyl (3aR, 4R, 5S, 5aR, 10bR, 13aR)-4-(acetyloxy)-3a-ethyl-9-[(1aS, 11S, 13S, 13aR)-1a-ethyl-11-(methoxycarbonyl)-1a, 4, 5, 10, 11, 12, 13, 13a-octahydro-2H-3, 13-methano-oxireno[9, 10]azacycloundecino[5, 4-b]indol-11-yl]-6-formyl-5-hydroxy-8-methoxy-3a, 4, 5, 5a, 6, 11, 12, 13a-octahydro-1H-indolizino[8, 1-cd]carbazole-5-carboxylate
InChIKeyGLDSBTCHEGZWCV-NVDFJPPOSA-N

02Structure identifiers

2D structurePubChem CID 76972843
Two-dimensional chemical structure of Vincristine Sulfate EP Impurity G / Formylleurosine (Free Base), CAS 54022-49-0
Two-dimensional structure for the PubChem identity linked to this record. Confirm the identifiers before analytical use.

The parsed structure contains 10 rings, includes aromatic atoms, includes aliphatic carbon, has 10 defined stereocentres. These statements are calculated from the published structure string.

Defined stereocentres10
Unassigned stereocentres1
Ring count10
Secondary amines0
Tertiary amines2
N-methyl amine sites0
SMILESCC[C@]12CN3CCC4=C([C@](C[C@@H](C3)[C@H]1O2)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)NC1=CC=CC=C41
InChINot listed
Formula from structureC46H54N4O10
Molecular weight from structure822.94 g/mol

03Stereochemistry

The published structure contains 10 defined and 1 unassigned tetrahedral stereocentres. The exact wedge and dash depiction is shown above.

Defined centres10Structure assigned
Unassigned centres1Structure unspecified
Assignment statusPartially assignedExact published identity
Tetrahedral upper bound≤ 2,048Before symmetry reduction

Published same-connectivity configurations

2 records

These records have the same connectivity, molecular formula and protonation layer, but a different complete InChIKey stereochemical layer. Only separately structure-linked records are shown.

Scope: The mathematical 2^n value is only an upper bound. Symmetry and other stereogenic elements can change the number of distinct stereoisomers. A hypothetical configuration is not published as a compound record without a verified structure identity.

04India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNO EXACT MATCH FOUNDCAS 54022-49-0 has no exact match in the reviewed published schedule.
SCOMETNO EXACT REVIEWED CAS MATCHCAS 54022-49-0 has no exact match in the reviewed SCOMET list.
Review date2026-08-01Recheck the current official instruments for the material, concentration, activity and date in question.

05Names and relationships

Associated parent compound

Vincristine

View API and impurity family

Other names

  • Vincristine Sulfate EP Impurity G (Free Base)
  • 4'-Desoxy-3'alpha, 4'alpha-epoxyvincristin
  • N-Demethyl-N-formylleurosine
  • Formylleurosine

Related records from the same parent family

06Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

07Sources