Chemical identity

Tenofovir Disoproxil Fumarate IP Impurity E/ Mono-POC Tenofovir 6-Isopropyl Carbamate

CAS 1244022-56-7 · C18H28N5O9P

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-29058
PubChem CID71750819
NameTenofovir Disoproxil Fumarate IP Impurity E/ Mono-POC Tenofovir 6-Isopropyl Carbamate
CAS RN1244022-56-7
Molecular formulaC18H28N5O9P
Molecular weight489.42 g/mol
IUPAC name(1-Methylethyl) (8R)-5-hydroxy-8-methyl-9-(6-{[(1-methylethoxy)carbonyl]amino}-9H-purin-9-yl)-5-oxo-2,4,7-trioxa-5-λ5-phosphanonanoate
InChIKeyCEFDJALYGKEXAQ-CYBMUJFWSA-N

02Structure identifiers

2D structurePubChem CID 71750819
Two-dimensional chemical structure of Tenofovir Disoproxil Fumarate IP Impurity E/ Mono-POC Tenofovir 6-Isopropyl Carbamate, CAS 1244022-56-7
Two-dimensional structure for the PubChem identity linked to this record. Confirm the identifiers before analytical use.

The parsed structure contains 2 rings, includes aromatic atoms, includes aliphatic carbon, has 1 defined stereocentre. These statements are calculated from the published structure string.

Defined stereocentres1
Unassigned stereocentres1
Ring count2
Secondary amines0
Tertiary amines0
N-methyl amine sites0
SMILESC[C@H](CN1C=NC2=C(N=CN=C21)NC(=O)OC(C)C)OCP(=O)(O)OCOC(=O)OC(C)C
InChINot listed
Formula from structureC18H28N5O9P
Molecular weight from structure489.42 g/mol

03Stereochemistry

The published structure contains 1 defined and 1 unassigned tetrahedral stereocentres. The exact wedge and dash depiction is shown above.

Defined centres1Structure assigned
Unassigned centres1Structure unspecified
Assignment statusPartially assignedExact published identity
Tetrahedral upper bound≤ 4Before symmetry reduction

Published same-connectivity configurations

1 record

These records have the same connectivity, molecular formula and protonation layer, but a different complete InChIKey stereochemical layer. Only separately structure-linked records are shown.

No additional structure-linked configuration with the same connectivity is currently present in the LazyChem dataset.

Scope: The mathematical 2^n value is only an upper bound. Symmetry and other stereogenic elements can change the number of distinct stereoisomers. A hypothetical configuration is not published as a compound record without a verified structure identity.

04India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNO EXACT MATCH FOUNDCAS 1244022-56-7 has no exact match in the reviewed published schedule.
SCOMETNO EXACT REVIEWED CAS MATCHCAS 1244022-56-7 has no exact match in the reviewed SCOMET list.
Review date2026-08-01Recheck the current official instruments for the material, concentration, activity and date in question.

05Names and relationships

Associated parent compound

Tenofovir

View API and impurity family

Other names

  • Tenofovir Disoproxil Fumarate IP Impurity E
  • Mono-POC Tenofovir 6-Isopropyl Carbamate
  • Isopropyl (9-((2R)-2-((hydroxy(((isopropoxycarbonyl)oxy)methoxy)phosphoryl)methoxy)propyl)-9H-purin-6-yl)carbamate
  • 1244022-56-7
  • UNII-BNM443XH9I
  • BNM443XH9I
  • [(2R)-1-[6-(Propan-2-yloxycarbonylamino)purin-9-yl]propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphinic acid
  • Tenofovir disoproxil fumarate impurity E
  • Tenofovir disoproxil fumarate impurity E [WHO-IP]
  • 2,4,7-Trioxa-5-phosphanonanoic acid, 5-hydroxy-8-methyl-9-(6-(((1-methylethoxy)carbonyl)amino)-9H-purin-9-yl)-, 1-methylethyl ester, 5-oxide, (8R)-
  • DTXSID40858143
  • Tenofovir disoproxil Impurity 49

Related records from the same parent family

06Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

07Sources