Chemical identity

Sotalol EP Impurity B / Sotalol Related Compound A

CAS 60735-85-5 · C12H18N2O3S

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-28367
PubChem CID11086835
NameSotalol EP Impurity B / Sotalol Related Compound A
CAS RN60735-85-5
Molecular formulaC12H18N2O3S
Molecular weight270.35 g/mol
IUPAC nameN-[4-[[(Propan-2-yl)amino]acetyl]phenyl]methanesulfonamide
InChIKeyBKXGLPPAZWSLEH-UHFFFAOYSA-N

02Structure identifiers

2D structurePubChem CID 11086835
Two-dimensional chemical structure of Sotalol EP Impurity B / Sotalol Related Compound A, CAS 60735-85-5
Two-dimensional structure for the PubChem identity linked to this record. Confirm the identifiers before analytical use.

The parsed structure contains 1 ring, includes aromatic atoms, includes aliphatic carbon. These statements are calculated from the published structure string.

Defined stereocentres0
Unassigned stereocentres0
Ring count1
Secondary amines1
Tertiary amines0
N-methyl amine sites0
SMILESCC(C)NCC(=O)C1=CC=C(C=C1)NS(=O)(=O)C
InChINot listed
Formula from structureC12H18N2O3S
Molecular weight from structure270.35 g/mol

03Possible N-nitroso structures

Shown for structural screening only. These candidates are not confirmed impurities, formation predictions or analytical findings.

Matched amine site1 candidate
Chemical structure of Sotalol EP Impurity B / Sotalol Related Compound A with the matched amine site highlighted in amber
Amber identifies the screened atom and adjacent bonds.
Possible structure candidateUnverified identity
First calculated possible N-nitroso structure derived from Sotalol EP Impurity B / Sotalol Related Compound A, with the new N-nitroso group highlighted in amber
The new N-N=O atoms and bonds are highlighted. No CAS number or compound name is assigned by this calculation.
Candidate 1Possible N-nitroso structural candidate
Calculated formula
C12H17N3O4S
Candidate SMILES
CC(C)N(CC(=O)c1ccc(NS(C)(=O)=O)cc1)N=O

Interpretation: A structural alert alone does not establish that a nitrosamine forms. Evaluate nitrite sources, amine reagents, pH, temperature, process sequence, purge and analytical evidence.

04India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNO EXACT MATCH FOUNDCAS 60735-85-5 has no exact match in the reviewed published schedule.
SCOMETNO EXACT REVIEWED CAS MATCHCAS 60735-85-5 has no exact match in the reviewed SCOMET list.
Review date2026-08-01Recheck the current official instruments for the material, concentration, activity and date in question.

05Names and relationships

Associated parent compound

Sotalol

View API and impurity family

Other names

  • Sotalol EP Impurity B
  • Sotalol Related Compound A
  • Oxo sotalol
  • 60735-85-5
  • UYF9Q60U7D
  • Sotalol hydrochloride specified impurity B [EP]
  • N-(4-(((1-Methylethyl)amino)acetyl)phenyl)methanesulfonamide
  • Methanesulfonamide, N-(4-(2-((1-methylethyl)amino)acetyl)phenyl)-
  • DTXSID60209552
  • SOTALOL HYDROCHLORIDE IMPURITY B [EP IMPURITY]
  • RefChem:857763
  • DTXCID10132043

Related records from the same parent family

06Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

07Sources