Chemical identity

Ranitidine EP Impurity B

CAS 72545-66-5 · C10H18N2OS.HCl

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-26724
PubChem CID18923808
NameRanitidine EP Impurity B
CAS RN72545-66-5
Molecular formulaC10H18N2OS.HCl
Molecular weight287.2 g/mol
IUPAC name2-[[[5-[(Dimethylamino)methyl]-furan-2-yl]methyl]sulfanyl]ethanamine hydrochloride
InChIKeyJNTOYGBZXJSVNI-UHFFFAOYSA-N

02Structure identifiers

2D structurePubChem CID 18923808
2D structure: Ranitidine EP Impurity B, CAS 72545-66-5
Structure of Ranitidine EP Impurity B (CAS 72545-66-5). LazyChem record. Source identity: PubChem CID 18923808. Confirm the identifiers before analytical use.Download structure image

Structure facts for this exact identity.

Molecular formulaC10H18N2OS.HCl
InChIKeyJNTOYGBZXJSVNI-UHFFFAOYSA-N
Ring count1
Defined stereocentres0
Unassigned stereocentres0
SMILESCN(C)CC1=CC=C(O1)CSCCN.Cl.Cl
InChIInChI=1S/C10H18N2OS.2ClH/c1-12(2)7-9-3-4-10(13-9)8-14-6-5-11;;/h3-4H,5-8,11H2,1-2H3;2*1H

03Possible N-nitroso structures

A record-level structural review indicates a possible N-nitroso candidate. This is not a confirmed impurity, formation prediction or analytical finding.

Possible structure candidateUnconfirmed identity
Possible N-nitroso structural candidate related to Ranitidine EP Impurity B, CAS 72545-66-5
No CAS number, formation claim or analytical confirmation is assigned.

A structural result alone does not establish that a nitrosamine forms. A process-specific and analytical assessment is required.

04India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNOT FOUND IN REVIEWED ENTRIESCAS 72545-66-5 was not found in the reviewed exact-identity entries. Generic, class, analogue, salt and isomer provisions were not evaluated.
SCOMETNOT FOUND IN REVIEWED CAS ENTRIESCAS 72545-66-5 was not found in the reviewed exact-CAS mapping. Generic and analogue entries were not evaluated.

05Names and relationships

Associated parent compound

Ranitidine

View API and impurity family

Other names

  • Ranitidine Aminoethyl Impurity
  • 5-{[(2-Aminoethyl)-thio]-methyl}-N,N-dimethyl-2-furanmethanamine dihydrochloride
  • 2-(((5-((Dimethylamino)methyl)furan-2-yl)methyl)thio)ethan-1-amine dihydrochloride
  • 2-([(5-Dimethylamino)Methylfuryl]Thio)Ethylamine Dihydrochloride
  • Ranitidine Related Compound A(2HCl Salt)
  • Ranitidine BP Impurity B(2HCl Salt)
  • Ranitidine EP Impurity B/ Ranitidine BP Impurity B/ Ranitidine Aminoethyl Impurity/ Ranitidine Related Compound A

Related records from the same parent family

06Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

07Sources