Chemical identity

Ramipril EP Impurity K / Ramipril Diketopiperazine Acid / Ramiprilat Diketopiperazine / Ramipril Diacid Dione

CAS 108736-10-3 · C21H26N2O4

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-26709
PubChem CID69267073
NameRamipril EP Impurity K / Ramipril Diketopiperazine Acid / Ramiprilat Diketopiperazine / Ramipril Diacid Dione
CAS RN108736-10-3
Molecular formulaC21H26N2O4
Molecular weight370.44 g/mol
IUPAC name(2S)-2-[(3S,5aS,8aS,9aS)-3-Methyl-1,4-dioxodecahydro-2H-cyclopenta[4,5] pyrrolo[1,2-a]pyrazin-2-yl]-4-phenylbutanoic acid
InChIKeyDZRWPCCIYKIPJW-HILJTLORSA-N

02Structure identifiers

2D structurePubChem CID 69267073
Two-dimensional chemical structure of Ramipril EP Impurity K / Ramipril Diketopiperazine Acid / Ramiprilat Diketopiperazine / Ramipril Diacid Dione, CAS 108736-10-3
Two-dimensional structure for the PubChem identity linked to this record. Confirm the identifiers before analytical use.

The parsed structure contains 4 rings, includes aromatic atoms, includes aliphatic carbon, has 5 defined stereocentres. These statements are calculated from the published structure string.

Defined stereocentres5
Unassigned stereocentres0
Ring count4
Secondary amines0
Tertiary amines0
N-methyl amine sites0
SMILESC[C@H]1C(=O)N2[C@H]3CCC[C@H]3C[C@H]2C(=O)N1[C@@H](CCC4=CC=CC=C4)C(=O)O
InChINot listed
Formula from structureC21H26N2O4
Molecular weight from structure370.44 g/mol

03Stereochemistry

The published structure contains 5 defined and 0 unassigned tetrahedral stereocentres. The exact wedge and dash depiction is shown above.

Defined centres5Structure assigned
Unassigned centres0Structure unspecified
Assignment statusFully assignedExact published identity
Tetrahedral upper bound≤ 32Before symmetry reduction

Published same-connectivity configurations

1 record

These records have the same connectivity, molecular formula and protonation layer, but a different complete InChIKey stereochemical layer. Only separately structure-linked records are shown.

No additional structure-linked configuration with the same connectivity is currently present in the LazyChem dataset.

Scope: The mathematical 2^n value is only an upper bound. Symmetry and other stereogenic elements can change the number of distinct stereoisomers. A hypothetical configuration is not published as a compound record without a verified structure identity.

04India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNO EXACT MATCH FOUNDCAS 108736-10-3 has no exact match in the reviewed published schedule.
SCOMETNO EXACT REVIEWED CAS MATCHCAS 108736-10-3 has no exact match in the reviewed SCOMET list.
Review date2026-08-01Recheck the current official instruments for the material, concentration, activity and date in question.

05Names and relationships

Associated parent compound

Ramipril

View API and impurity family

Other names

  • Ramipril EP Impurity K
  • Ramipril Diketopiperazine Acid / Ramiprilat Diketopiperazine / Ramipril Diacid Dione
  • Ramipril diketopiperazine acid
  • 108736-10-3
  • AN6P6O95UU
  • Ramipril Impurity K
  • Ramipril impurity K [EP]
  • (2S)-2-[(2S,6S,8S,11S)-11-methyl-9,12-dioxo-1,10-diazatricyclo[6.4.0.02,6]dodecan-10-yl]-4-phenylbutanoic acid
  • RAMIPRIL IMPURITY K [EP IMPURITY]
  • (2S)-2-((3S,5aS,8aS,9aS)-3-Methyl-1,4-dioxodecahydro-2H-cyclopenta(4,5)pyrrolo(1,2-a)pyrazin-2-yl)-4-phenylbutanoic acid
  • 2H-CYCLOPENTA(4,5)PYRROLO(1,2-A)PYRAZINE-2-ACETIC ACID, DECAHYDRO-3-METHYL-1,4-DIOXO-.ALPHA.-(2-PHENYLETHYL)-, (.ALPHA.S,3S,5AS,8AS,9AS)-
  • RefChem:875113

Related records from the same parent family

06Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

07Sources