Chemical identity

Pomalidomide N4-Hydroxy Impurity / Pomalidomide Impurity B

CAS 497147-11-2 · C13H11N3O5

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-25656
PubChem CID135506537
NamePomalidomide N4-Hydroxy Impurity / Pomalidomide Impurity B
CAS RN497147-11-2
Molecular formulaC13H11N3O5
Molecular weight289.24 g/mol
IUPAC name2-(2,6-Dioxopiperidin-3-yl)-4-(hydroxyamino)isoindoline-1,3-dione
InChIKeyRMKXSRCTDDVULP-UHFFFAOYSA-N

02Structure identifiers

2D structurePubChem CID 135506537
2D structure: Pomalidomide N4-Hydroxy Impurity / Pomalidomide Impurity B, CAS 497147-11-2
Structure of Pomalidomide N4-Hydroxy Impurity / Pomalidomide Impurity B (CAS 497147-11-2). LazyChem record. Source identity: PubChem CID 135506537. Confirm the identifiers before analytical use.Download structure image

Structure facts for this exact identity.

Molecular formulaC13H11N3O5
InChIKeyRMKXSRCTDDVULP-UHFFFAOYSA-N
Ring count3
Defined stereocentres0
Unassigned stereocentres1
SMILESC1CC(=O)NC(=O)C1N2C(=C3C=CC=C(C3=C2O)N=O)O
InChIInChI=1S/C13H11N3O5/c17-9-5-4-8(11(18)14-9)16-12(19)6-2-1-3-7(15-21)10(6)13(16)20/h1-3,8,19-20H,4-5H2,(H,14,17,18)

03Stereochemistry

The published structure contains 0 defined and 1 unassigned tetrahedral stereocentre. The exact wedge-and-dash depiction is shown above.

Defined stereocentres02D structure
Unassigned stereocentres12D structure
Assignment statusUnassignedExact published identity
Tetrahedral upper bound≤ 2Before symmetry reduction

Published same-connectivity configurations

1 record

These records have the same connectivity, molecular formula and protonation layer, but a different complete InChIKey stereochemical layer. Only separately structure-linked records are shown.

No additional structure-linked configuration with the same connectivity is currently present in the LazyChem dataset.

Scope: The mathematical 2^n value is only an upper bound. Symmetry and other stereogenic elements can change the number of distinct stereoisomers. A hypothetical configuration is not published as a compound record without a verified structure identity.

04India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNOT FOUND IN REVIEWED ENTRIESCAS 497147-11-2 was not found in the reviewed exact-identity entries. Generic, class, analogue, salt and isomer provisions were not evaluated.
SCOMETNOT FOUND IN REVIEWED CAS ENTRIESCAS 497147-11-2 was not found in the reviewed exact-CAS mapping. Generic and analogue entries were not evaluated.

05Names and relationships

Associated parent compound

Pomalidomide

View API and impurity family

Other names

  • Pomalidomide N4-Hydroxy Impurity
  • Pomalidomide Impurity B
  • 2-(2,6-Dioxo-3-piperidinyl)-4-(hydroxyamino)-1H-isoindole-1,3(2H)-dione
  • N-Hydroxy Pomalidomide
  • 2-?(2,?6-?Dioxo-?3-?piperidinyl)?-?4-?(hydroxyamino)?-1H-?isoindole-?1,?3(2H)?-?dione
  • 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(hydroxyamino)- (9CI, ACI)
  • 2-(2,6-Dioxo-3-piperidinyl)-4-(hydroxyamino)-1H-isoindole-1,3(2H)-dione (ACI)
  • 2-(2,6-dioxo-3-piperidyl)-4-(hydroxyamino)isoindoline-1,3-dione

Related records from the same parent family

06Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

07Sources