API and parent drug

Dabrafenib

CAS 1195765-45-7 · C23H20F3N5O2S2 · 4 related records

01API identity and structure

2D structurePubChem CID 44462760
2D structure: Dabrafenib, CAS 1195765-45-7
Structure of Dabrafenib (CAS 1195765-45-7). LazyChem record. Source identity: PubChem CID 44462760. Confirm the identifiers before analytical use.Download structure image
API / medicine nameDabrafenib
CAS RN1195765-45-7
PubChem CID44462760
Molecular formulaC23H20F3N5O2S2
Molecular weight519.6 g/mol
IUPAC nameN-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide
Defined stereocentres0
Unassigned stereocentres0
SMILESCC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F
InChINot listed
InChIKeyBFSMGDJOXZAERB-UHFFFAOYSA-N

02Structural nitrosamine screen

Record-level resultNo candidate is published

No record-level structural candidate is currently published for this identity.

This result does not predict manufacturing conditions, formation, analytical findings or absence of risk. A process-specific assessment is required.

03India status for this compound

The result below applies only to this exact compound identity and CAS number.

NDPS / RCSNOT FOUND IN REVIEWED ENTRIESNo exact reviewed identity entry was found. Generic, class, analogue, salt and isomer provisions were not evaluated. Confirm the current official schedule before a regulatory decision.
SCOMETNOT FOUND IN REVIEWED CAS ENTRIESCAS 1195765-45-7 was not found in the reviewed exact-CAS mapping. Generic and analogue entries were not evaluated.

05Sources