Chemical identity

Palbociclib N-Formyl Impurity / Palbociclib N-Aldehyde

CAS 2174002-16-3 · C25H29N7O3

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-24569
PubChem CID154634180
NamePalbociclib N-Formyl Impurity / Palbociclib N-Aldehyde
CAS RN2174002-16-3
Molecular formulaC25H29N7O3
Molecular weight475.54 g/mol
IUPAC name4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde
InChIKeyKVICSWHDXLNVAO-UHFFFAOYSA-N

02Structure identifiers

2D structurePubChem CID 154634180
2D structure: Palbociclib N-Formyl Impurity / Palbociclib N-Aldehyde, CAS 2174002-16-3
Structure of Palbociclib N-Formyl Impurity / Palbociclib N-Aldehyde (CAS 2174002-16-3). LazyChem record. Source identity: PubChem CID 154634180. Confirm the identifiers before analytical use.Download structure image

Structure facts for this exact identity.

Molecular formulaC25H29N7O3
InChIKeyKVICSWHDXLNVAO-UHFFFAOYSA-N
Ring count5
Defined stereocentres0
Unassigned stereocentres0
SMILESCC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCN(CC4)C=O)C5CCCC5)C(=O)C
InChIInChI=1S/C25H29N7O3/c1-16-20-14-27-25(28-21-8-7-19(13-26-21)31-11-9-30(15-33)10-12-31)29-23(20)32(18-5-3-4-6-18)24(35)22(16)17(2)34/h7-8,13-15,18H,3-6,9-12H2,1-2H3,(H,26,27,28,29)

03Possible N-nitroso structures

A record-level structural review indicates a possible N-nitroso candidate. This is not a confirmed impurity, formation prediction or analytical finding.

Possible structure candidateUnconfirmed identity
Possible N-nitroso structural candidate related to Palbociclib N-Formyl Impurity / Palbociclib N-Aldehyde, CAS 2174002-16-3
No CAS number, formation claim or analytical confirmation is assigned.

A structural result alone does not establish that a nitrosamine forms. A process-specific and analytical assessment is required.

04India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNOT FOUND IN REVIEWED ENTRIESCAS 2174002-16-3 was not found in the reviewed exact-identity entries. Generic, class, analogue, salt and isomer provisions were not evaluated.
SCOMETNOT FOUND IN REVIEWED CAS ENTRIESCAS 2174002-16-3 was not found in the reviewed exact-CAS mapping. Generic and analogue entries were not evaluated.

05Names and relationships

Associated parent compound

Palbociclib

View API and impurity family

Other names

  • Palbociclib N-Formyl Impurity
  • Palbociclib N-Aldehyde
  • 4-[6-[(6-Acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxaldehyde
  • N-Formyl Palbociclib
  • Palbociclib Impurity 025
  • UNII-NJB3FNK33C
  • 4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde
  • 1-Piperazinecarboxaldehyde, 4-(6-((6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido(2,3-d)pyrimidin-2-yl)amino)-3-pyridinyl)-
  • 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde (Palbociclib Impurity
  • 4-[6-[(6-Acetyl-8-cyclopentyl-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carbaldehyde

Related records from the same parent family

06Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

07Sources