Chemical identity

Osimertinib N-Methylacrylamide Impurity

CAS 2850389-35-2 · C30H33N7O3

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-24305
PubChem CID162515208
NameOsimertinib N-Methylacrylamide Impurity
CAS RN2850389-35-2
Molecular formulaC30H33N7O3
Molecular weight539.6 g/mol
IUPAC nameN-(2-((2-Acrylamido-5-methoxy-4-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)(methyl)amino)ethyl)-N-methylacrylamide
InChIKeyDSBVGSFDEAXNDQ-UHFFFAOYSA-N

02Structure identifiers

2D structurePubChem CID 162515208
Two-dimensional chemical structure of Osimertinib N-Methylacrylamide Impurity, CAS 2850389-35-2
Two-dimensional structure for the PubChem identity linked to this record. Confirm the identifiers before analytical use.

The parsed structure contains 4 rings, includes aromatic atoms, includes aliphatic carbon. These statements are calculated from the published structure string.

Defined stereocentres0
Unassigned stereocentres0
Ring count4
Secondary amines1
Tertiary amines1
N-methyl amine sites1
SMILESCN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C(=O)C=C)OC
InChINot listed
Formula from structureC30H33N7O3
Molecular weight from structure539.6 g/mol

03Possible N-nitroso structures

Shown for structural screening only. These candidates are not confirmed impurities, formation predictions or analytical findings.

Matched amine site3 candidates
Chemical structure of Osimertinib N-Methylacrylamide Impurity with the matched amine site highlighted in amber
Amber identifies the screened atom and adjacent bonds.
Possible structure candidateUnverified identity
First calculated possible N-nitroso structure derived from Osimertinib N-Methylacrylamide Impurity, with the new N-nitroso group highlighted in amber
The new N-N=O atoms and bonds are highlighted. No CAS number or compound name is assigned by this calculation.
Candidate 1Possible N-nitroso structural candidate
Calculated formula
C30H32N8O4
Candidate SMILES
C=CC(=O)Nc1cc(N(N=O)c2nccc(-c3cn(C)c4ccccc34)n2)c(OC)cc1N(C)CCN(C)C(=O)C=C
Candidate 2Possible N-nitroso structural candidate
Calculated formula
C29H30N8O4
Candidate SMILES
C=CC(=O)Nc1cc(Nc2nccc(-c3cn(N=O)c4ccccc34)n2)c(OC)cc1N(C)CCN(C)C(=O)C=C
Candidate 3Possible N-nitroso structural candidate
Calculated formula
C29H30N8O4
Candidate SMILES
C=CC(=O)Nc1cc(Nc2nccc(-c3cn(C)c4ccccc34)n2)c(OC)cc1N(CCN(C)C(=O)C=C)N=O

Interpretation: A structural alert alone does not establish that a nitrosamine forms. Evaluate nitrite sources, amine reagents, pH, temperature, process sequence, purge and analytical evidence.

04India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNO EXACT MATCH FOUNDCAS 2850389-35-2 has no exact match in the reviewed published schedule.
SCOMETNO EXACT REVIEWED CAS MATCHCAS 2850389-35-2 has no exact match in the reviewed SCOMET list.
Review date2026-08-01Recheck the current official instruments for the material, concentration, activity and date in question.

05Names and relationships

Associated parent compound

Osimertinib

View API and impurity family

Other names

  • Osimertinib Impurity 50
  • 2850389-35-2

Related records from the same parent family

06Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

07Sources