Chemical identity

Nepafenac Related Compound A / Nepafenac Inhouse Impurity E / Nepafenac Hydroxybenzyl Impurity

CAS 1246956-18-2 · C15H16N2O2

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-23265
PubChem CID67143888
NameNepafenac Related Compound A / Nepafenac Inhouse Impurity E / Nepafenac Hydroxybenzyl Impurity
CAS RN1246956-18-2
Molecular formulaC15H16N2O2
Molecular weight256.3 g/mol
IUPAC name(2-{2-Amino-3-[hydroxy(phenyl)methyl]phenyl}acetamide)
InChIKeyLXWNZCRPDAGUHQ-UHFFFAOYSA-N

02Structure identifiers

2D structurePubChem CID 67143888
Two-dimensional chemical structure of Nepafenac Related Compound A / Nepafenac Inhouse Impurity E / Nepafenac Hydroxybenzyl Impurity, CAS 1246956-18-2
Two-dimensional structure for the PubChem identity linked to this record. Confirm the identifiers before analytical use.

The parsed structure contains 2 rings, includes aromatic atoms, includes aliphatic carbon. These statements are calculated from the published structure string.

Defined stereocentres0
Unassigned stereocentres1
Ring count2
Secondary amines0
Tertiary amines0
N-methyl amine sites0
SMILESC1=CC=C(C=C1)C(C2=CC=CC(=C2N)CC(=O)N)O
InChINot listed
Formula from structureC15H16N2O2
Molecular weight from structure256.3 g/mol

03Stereochemistry

The published structure contains 0 defined and 1 unassigned tetrahedral stereocentre. The exact wedge and dash depiction is shown above.

Defined centres0Structure assigned
Unassigned centres1Structure unspecified
Assignment statusUnassignedExact published identity
Tetrahedral upper bound≤ 2Before symmetry reduction

Published same-connectivity configurations

1 record

These records have the same connectivity, molecular formula and protonation layer, but a different complete InChIKey stereochemical layer. Only separately structure-linked records are shown.

No additional structure-linked configuration with the same connectivity is currently present in the LazyChem dataset.

Scope: The mathematical 2^n value is only an upper bound. Symmetry and other stereogenic elements can change the number of distinct stereoisomers. A hypothetical configuration is not published as a compound record without a verified structure identity.

04India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNO EXACT MATCH FOUNDCAS 1246956-18-2 has no exact match in the reviewed published schedule.
SCOMETNO EXACT REVIEWED CAS MATCHCAS 1246956-18-2 has no exact match in the reviewed SCOMET list.
Review date2026-08-01Recheck the current official instruments for the material, concentration, activity and date in question.

05Names and relationships

Associated parent compound

Nepafenac

View API and impurity family

Other names

  • Nepafenac Inhouse Impurity E
  • Nepafenac Hydroxybenzyl Impurity
  • 2-{2-Amino-3-[hydroxy(phenyl)methyl]phenyl}acetamide
  • 3-Desbenzoyl-3-hydroxybenzyl nepafenac
  • 1246956-18-2
  • Q9PE78QS43
  • 2-Amino-3-(hydroxyphenylmethyl)benzeneacetamide
  • Benzeneacetamide, 2-amino-3-(hydroxyphenylmethyl)-
  • RefChem:197554
  • 940-021-0
  • UNII-Q9PE78QS43
  • SCHEMBL1740322

Related records from the same parent family

06Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

07Sources