Chemical identity

Naloxone EP Impurity D/ 7,8-Didehydro Naloxone

CAS 26451-92-3 · C19H19NO4

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-23056
PubChem CID9897757
NameNaloxone EP Impurity D/ 7,8-Didehydro Naloxone
CAS RN26451-92-3
Molecular formulaC19H19NO4
Molecular weight325.36 g/mol
IUPAC name7,8-Didehydro Naloxone; 7,8-Didehydro-4,5α-epoxy-3,14-dihydroxy-17-(prop-2-enyl)morphinan-6-one
InChIKeyVHFYKBURRFNDQL-GRGSLBFTSA-N

02Structure identifiers

2D structurePubChem CID 9897757
Two-dimensional chemical structure of Naloxone EP Impurity D/ 7,8-Didehydro Naloxone, CAS 26451-92-3
Two-dimensional structure for the PubChem identity linked to this record. Confirm the identifiers before analytical use.

The parsed structure contains 5 rings, includes aromatic atoms, includes aliphatic carbon, has 4 defined stereocentres. These statements are calculated from the published structure string.

Defined stereocentres4
Unassigned stereocentres0
Ring count5
Secondary amines0
Tertiary amines1
N-methyl amine sites0
SMILESC=CCN1CC[C@]23[C@@H]4C(=O)C=C[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O
InChINot listed
Formula from structureC19H19NO4
Molecular weight from structure325.36 g/mol

03Stereochemistry

The published structure contains 4 defined and 0 unassigned tetrahedral stereocentres. The exact wedge and dash depiction is shown above.

Defined centres4Structure assigned
Unassigned centres0Structure unspecified
Assignment statusFully assignedExact published identity
Tetrahedral upper bound≤ 16Before symmetry reduction

Published same-connectivity configurations

1 record

These records have the same connectivity, molecular formula and protonation layer, but a different complete InChIKey stereochemical layer. Only separately structure-linked records are shown.

No additional structure-linked configuration with the same connectivity is currently present in the LazyChem dataset.

Scope: The mathematical 2^n value is only an upper bound. Symmetry and other stereogenic elements can change the number of distinct stereoisomers. A hypothetical configuration is not published as a compound record without a verified structure identity.

04India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNO EXACT MATCH FOUNDCAS 26451-92-3 has no exact match in the reviewed published schedule.
SCOMETNO EXACT REVIEWED CAS MATCHCAS 26451-92-3 has no exact match in the reviewed SCOMET list.
Review date2026-08-01Recheck the current official instruments for the material, concentration, activity and date in question.

05Names and relationships

Associated parent compound

Naloxone

View associated product family

Other names

  • Naloxone EP Impurity D
  • 7, 8-Didehydro Naloxone
  • (5alpha)-7,8-Didehydro-4,5-epoxy-3,14-dihydroxy-17-(2-propen-1-yl)morphinan-6-one
  • 26451-92-3
  • 3R6GHX7MRE
  • Naloxone hydrochloride dihydrate impurity D [EP]
  • Morphinan-6-one, 7,8-didehydro-4,5-epoxy-3,14-dihydroxy-17-(2-propen-1-yl)-, (5alpha)-
  • NALOXONE HYDROCHLORIDE DIHYDRATE IMPURITY D [EP IMPURITY]
  • RefChem:196514
  • Naloxone hydrochloride dihydrate impurity D
  • UNII-3R6GHX7MRE
  • 7,8-Didehydro Naloxone (1.0 mg/mL in Acetonitrile)

Related records from the same parent family

06Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

07Sources