Chemical identity

Meropenem EP Impurity A

CAS 1053703-36-8 · C17H27N3O6S

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-19734
PubChem CID10069633
NameMeropenem EP Impurity A
CAS RN1053703-36-8
Molecular formulaC17H27N3O6S
Molecular weight401.5 g/mol
IUPAC name(4R,5S)-5-[(1S,2R)-1-carboxy-2-hydroxypropyl]-3-[[(3S,5S)-5-[(dimethylamino)carbonyl]pyrrolidin-3-yl]sulfanyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid
InChIKeyILVWWUFTACAPIZ-PQTSNVLCSA-N

02Structure identifiers

2D structurePubChem CID 10069633
2D structure: Meropenem EP Impurity A, CAS 1053703-36-8
Structure of Meropenem EP Impurity A (CAS 1053703-36-8). LazyChem record. Source identity: PubChem CID 10069633. Confirm the identifiers before analytical use.Download structure image

Structure facts for this exact identity.

Molecular formulaC17H27N3O6S
InChIKeyILVWWUFTACAPIZ-PQTSNVLCSA-N
Ring count2
Defined stereocentres6
Unassigned stereocentres0
SMILESC[C@@H]1[C@@H](NC(=C1S[C@H]2C[C@H](NC2)C(=O)N(C)C)C(=O)O)[C@@H]([C@@H](C)O)C(=O)O
InChIInChI=1S/C17H27N3O6S/c1-7-12(11(8(2)21)16(23)24)19-13(17(25)26)14(7)27-9-5-10(18-6-9)15(22)20(3)4/h7-12,18-19,21H,5-6H2,1-4H3,(H,23,24)(H,25,26)/t7-,8-,9+,10+,11-,12-/m1/s1

03Stereochemistry

The published structure contains 6 defined and 0 unassigned tetrahedral stereocentres. The exact wedge-and-dash depiction is shown above.

Defined stereocentres62D structure
Unassigned stereocentres02D structure
Assignment statusFully assignedExact published identity
Tetrahedral upper bound≤ 64Before symmetry reduction

Published same-connectivity configurations

1 record

These records have the same connectivity, molecular formula and protonation layer, but a different complete InChIKey stereochemical layer. Only separately structure-linked records are shown.

No additional structure-linked configuration with the same connectivity is currently present in the LazyChem dataset.

Scope: The mathematical 2^n value is only an upper bound. Symmetry and other stereogenic elements can change the number of distinct stereoisomers. A hypothetical configuration is not published as a compound record without a verified structure identity.

04Possible N-nitroso structures

A record-level structural review indicates a possible N-nitroso candidate. This is not a confirmed impurity, formation prediction or analytical finding.

Possible structure candidateUnconfirmed identity
Possible N-nitroso structural candidate related to Meropenem EP Impurity A, CAS 1053703-36-8
No CAS number, formation claim or analytical confirmation is assigned.

A structural result alone does not establish that a nitrosamine forms. A process-specific and analytical assessment is required.

05India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNOT FOUND IN REVIEWED ENTRIESCAS 1053703-36-8 was not found in the reviewed exact-identity entries. Generic, class, analogue, salt and isomer provisions were not evaluated.
SCOMETNOT FOUND IN REVIEWED CAS ENTRIESCAS 1053703-36-8 was not found in the reviewed exact-CAS mapping. Generic and analogue entries were not evaluated.

06Names and relationships

Associated parent compound

Meropenem

View API and impurity family

Other names

  • Meropenem Open-Ring Impurity
  • Meropenem Open Ring (Na Salt)
  • Meropenem Open Ring (2Na Salt)
  • Meropenem open ring
  • UNII-4MC3K7LDC6
  • (4R,5S)-5-((1S,2R)-1-Carboxy-2-hydroxypropyl)-3-(((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl)thio)-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid
  • Meropenem trihydrate impurity A [EP]
  • (4R,5S)-5-((1S,2R)-1-Carboxy-2-hydroxypropyl)-3-(((3S,5S)-5-((dimethylamino)carbonyl)pyrrolidin-3-yl)sulfanyl)-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid
  • MEROPENEM TRIHYDRATE IMPURITY A [EP IMPURITY]
  • (.ALPHA.S,2S,3R)-5-CARBOXY-4-(((3S,5S)-5-((DIMETHYLAMINO)CARBONYL)-3-PYRROLIDINYL)THIO)-2,3-DIHYDRO-.ALPHA.-((1R)-1-HYDROXYETHYL)-3-METHYL-1H-PYRROLE-2-ACETIC ACID

Related records from the same parent family

07Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

08Sources