Chemical identity

1-(2-chloro-4-((6-cyano-7-methoxyquinolin-4-yl)oxy)phenyl)-3-cyclopropylurea

CAS 2380197-89-5 · C17H14ClN3O3

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-18274
PubChem CID141761012
Name1-(2-chloro-4-((6-cyano-7-methoxyquinolin-4-yl)oxy)phenyl)-3-cyclopropylurea
CAS RN2380197-89-5
Molecular formulaC17H14ClN3O3
Molecular weight343.77 g/mol
IUPAC name4-((2-chloro-4-hydroxyphenyl)amino)-7-methoxyquinoline-6-carboxamide
InChIKeyVHAKAVTXAHZIIE-UHFFFAOYSA-N

02Structure identifiers

2D structurePubChem CID 141761012
2D structure: 1-(2-chloro-4-((6-cyano-7-methoxyquinolin-4-yl)oxy)phenyl)-3-cyclopropylurea, CAS 2380197-89-5
Structure of 1-(2-chloro-4-((6-cyano-7-methoxyquinolin-4-yl)oxy)phenyl)-3-cyclopropylurea (CAS 2380197-89-5). LazyChem record. Source identity: PubChem CID 141761012. Confirm the identifiers before analytical use.Download structure image

Structure facts for this exact identity.

Molecular formulaC17H14ClN3O3
InChIKeyVHAKAVTXAHZIIE-UHFFFAOYSA-N
Ring count3
Defined stereocentres0
Unassigned stereocentres0
SMILESCOC1=CC2=NC=CC(=C2C=C1C(=O)N)NC3=C(C=C(C=C3)O)Cl
InChIInChI=1S/C17H14ClN3O3/c1-24-16-8-15-10(7-11(16)17(19)23)13(4-5-20-15)21-14-3-2-9(22)6-12(14)18/h2-8,22H,1H3,(H2,19,23)(H,20,21)

03Possible N-nitroso structures

A record-level structural review indicates a possible N-nitroso candidate. This is not a confirmed impurity, formation prediction or analytical finding.

Possible structure candidateUnconfirmed identity
Possible N-nitroso structural candidate related to 1-(2-chloro-4-((6-cyano-7-methoxyquinolin-4-yl)oxy)phenyl)-3-cyclopropylurea, CAS 2380197-89-5
No CAS number, formation claim or analytical confirmation is assigned.

A structural result alone does not establish that a nitrosamine forms. A process-specific and analytical assessment is required.

04India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNOT FOUND IN REVIEWED ENTRIESCAS 2380197-89-5 was not found in the reviewed exact-identity entries. Generic, class, analogue, salt and isomer provisions were not evaluated.
SCOMETNOT FOUND IN REVIEWED CAS ENTRIESCAS 2380197-89-5 was not found in the reviewed exact-CAS mapping. Generic and analogue entries were not evaluated.

05Names and relationships

Associated parent compound

Lenvatinib

View API and impurity family

Other names

  • Lenvatinib Impurity 8
  • 4-((2-Chloro-4-hydroxyphenyl)amino)-7-methoxyquinoline-6-carboxamide
  • 4-[(2-Chloro-4-hydroxyphenyl)amino]-7-methoxy-6-quinolinecarboxamide
  • 6-Quinolinecarboxamide, 4-[(2-chloro-4-hydroxyphenyl)amino]-7-methoxy-

Related records from the same parent family

06Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

07Sources