Chemical identity
Dasatinib Dehydroxy Ethyl Impurity / N-Deshydroxyethyl Dasatinib / Dasatinib Metabolite M4 / Dasatinib Related Compound B
CAS 910297-51-7 · C20H22ClN7OS
01Identity
Identifiers and names for this exact compound. Empty fields are left unassigned.
| Lazychem ID | LC-12035 |
|---|---|
| PubChem CID | 11669430 |
| Name | Dasatinib Dehydroxy Ethyl Impurity / N-Deshydroxyethyl Dasatinib / Dasatinib Metabolite M4 / Dasatinib Related Compound B |
| CAS RN | 910297-51-7 |
| Molecular formula | C20H22ClN7OS |
| Molecular weight | 443.95 g/mol |
| IUPAC name | N-(2-Chloro-6-methylphenyl)-2-[[2-methyl-6-(1-piperazinyl)-4-pyrimidinyl] amino]-5-thiazolecarboxamide |
| InChIKey | DOBZFFWLHXORTB-UHFFFAOYSA-N |
02Structure identifiers
Structure facts for this exact identity.
| Molecular formula | C20H22ClN7OS |
|---|---|
| InChIKey | DOBZFFWLHXORTB-UHFFFAOYSA-N |
| Ring count | 4 |
| Defined stereocentres | 0 |
| Unassigned stereocentres | 0 |
| SMILES | O=C(C1=CN=C(NC2=NC(C)=NC(N3CCNCC3)=C2)S1)NC4=C(C)C=CC=C4Cl |
|---|---|
| InChI | InChI=1S/C20H22ClN7OS/c1-12-4-3-5-14(21)18(12)27-19(29)15-11-23-20(30-15)26-16-10-17(25-13(2)24-16)28-8-6-22-7-9-28/h3-5,10-11,22H,6-9H2,1-2H3,(H,27,29)(H,23,24,25,26) |
03Possible N-nitroso structures
A record-level structural review indicates a possible N-nitroso candidate. This is not a confirmed impurity, formation prediction or analytical finding.
A structural result alone does not establish that a nitrosamine forms. A process-specific and analytical assessment is required.
04India status for this compound
These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.
| NDPS / RCS | NOT FOUND IN REVIEWED ENTRIES | CAS 910297-51-7 was not found in the reviewed exact-identity entries. Generic, class, analogue, salt and isomer provisions were not evaluated. |
|---|---|---|
| SCOMET | NOT FOUND IN REVIEWED CAS ENTRIES | CAS 910297-51-7 was not found in the reviewed exact-CAS mapping. Generic and analogue entries were not evaluated. |
- Narcotic Drugs and Psychotropic Substances Act, 1985, ScheduleDepartment of Revenue, Government of India · source version 1985-09-16
- Controlled-substances notifications and amendmentsDepartment of Revenue, Government of India · source version 2026-03-11
- Appendix 3, SCOMET ListDirectorate General of Foreign Trade, Government of India · source version 2024-09-02
05Names and relationships
Associated parent compound
Dasatinib
View API and impurity familyOther names
- Dasatinib Dehydroxy Ethyl Impurity
- N-Deshydroxyethyl Dasatinib
- Dasatinib Metabolite M4
- Dasatinib Related Compound B
06Documented history
Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.
No verified discovery, first report, occurrence, use or issue event is currently available for this identity.
07Sources
- S01PubChem compound record, CID 11669430
Names and machine-readable chemical identity properties.
- S02NCBI website and molecular data policies
Reuse policy for NCBI molecular data. This page does not reproduce vendor descriptions or contributed narrative text.
- S03Narcotic Drugs and Psychotropic Substances Act, 1985, Schedule
Department of Revenue, Government of India. Used for the exact-compound India status shown on this page.
- S04Controlled-substances notifications and amendments
Department of Revenue, Government of India. Used for the exact-compound India status shown on this page.
- S05Appendix 3, SCOMET List
Directorate General of Foreign Trade, Government of India. Used for the exact-compound India status shown on this page.