Chemical identity

Cyclizine Impurity A

CAS 109-01-3 · C5H12N2

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-11519
PubChem CID53167
NameCyclizine Impurity A
CAS RN109-01-3
Molecular formulaC5H12N2
Molecular weight100.16
IUPAC name1-Methyl-1,4-piperazine
InChIKeyPVOAHINGSUIXLS-UHFFFAOYSA-N

02Structure identifiers

2D structurePubChem CID 53167
Two-dimensional chemical structure of Cyclizine Impurity A, CAS 109-01-3
Two-dimensional structure for the PubChem identity linked to this record. Confirm the identifiers before analytical use.

The parsed structure contains 1 ring, includes aliphatic carbon. These statements are calculated from the published structure string.

Defined stereocentres0
Unassigned stereocentres0
Ring count1
Secondary amines1
Tertiary amines1
N-methyl amine sites1
SMILESCN1CCNCC1
InChINot listed
Formula from structureC5H12N2
Molecular weight from structure100.16

03Possible N-nitroso structures

Shown for structural screening only. These candidates are not confirmed impurities, formation predictions or analytical findings.

Matched amine site2 candidates
Chemical structure of Cyclizine Impurity A with the matched amine site highlighted in amber
Amber identifies the screened atom and adjacent bonds.
Possible structure candidateUnverified identity
First calculated possible N-nitroso structure derived from Cyclizine Impurity A, with the new N-nitroso group highlighted in amber
The new N-N=O atoms and bonds are highlighted. No CAS number or compound name is assigned by this calculation.
Candidate 1Possible N-nitroso structural candidate
Calculated formula
C5H11N3O
Candidate SMILES
CN1CCN(N=O)CC1
Candidate 2Possible N-nitroso structural candidate
Calculated formula
C4H9N3O
Candidate SMILES
O=NN1CCNCC1

Interpretation: A structural alert alone does not establish that a nitrosamine forms. Evaluate nitrite sources, amine reagents, pH, temperature, process sequence, purge and analytical evidence.

04India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNO EXACT MATCH FOUNDCAS 109-01-3 has no exact match in the reviewed published schedule.
SCOMETNO EXACT REVIEWED CAS MATCHCAS 109-01-3 has no exact match in the reviewed SCOMET list.
Review date2026-08-01Recheck the current official instruments for the material, concentration, activity and date in question.

05Names and relationships

Associated parent compound

Cyclizine; Imatinib; Piperazine

View API and impurity family

Other names

  • Imatinib EP Impurity G/ Cyclizine EP Impurity A/ Diethylcarbamazine EP Impurity A/ Pirenzepine EP Impurity D / N-Methylpiperazine
  • Cyclizine EP Impurity A
  • Diethylcarbamazine EP Impurity A
  • Pirenzepine EP Impurity D
  • 1-Methyl-1, 4-piperazine
  • N-Methylpiperazine
  • NSC 30195
  • NSC 30675
  • Imatinib EP Impurity G
  • 1-Methylpiperazine
  • 109-01-3
  • PIPERAZINE, 1-METHYL-

Related records from the same parent family

06Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

07Sources