Chemical identity

Colchicine EP Impurity F/ Colchicine BP Impurity F/ Colchiceine

CAS 477-27-0 · C21H23NO6

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-11395
PubChem CID234105
NameColchicine EP Impurity F/ Colchicine BP Impurity F/ Colchiceine
CAS RN477-27-0
Molecular formulaC21H23NO6
Molecular weight385.41 g/mol
IUPAC nameN-[(7S,12aM)-10-Hydroxy-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide
InChIKeyPRGILOMAMBLWNG-HNNXBMFYSA-N

02Structure identifiers

2D structurePubChem CID 234105
Two-dimensional chemical structure of Colchicine EP Impurity F/ Colchicine BP Impurity F/ Colchiceine, CAS 477-27-0
Two-dimensional structure for the PubChem identity linked to this record. Confirm the identifiers before analytical use.

The parsed structure contains 3 rings, includes aromatic atoms, includes aliphatic carbon, has 1 defined stereocentre. These statements are calculated from the published structure string.

Defined stereocentres1
Unassigned stereocentres0
Ring count3
Secondary amines0
Tertiary amines0
N-methyl amine sites0
SMILESCC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)O)OC)OC)OC
InChINot listed
Formula from structureC21H23NO6
Molecular weight from structure385.41 g/mol

03Stereochemistry

The published structure contains 1 defined and 0 unassigned tetrahedral stereocentre. The exact wedge and dash depiction is shown above.

Defined centres1Structure assigned
Unassigned centres0Structure unspecified
Assignment statusFully assignedExact published identity
Tetrahedral upper bound≤ 2Before symmetry reduction

Published same-connectivity configurations

1 record

These records have the same connectivity, molecular formula and protonation layer, but a different complete InChIKey stereochemical layer. Only separately structure-linked records are shown.

No additional structure-linked configuration with the same connectivity is currently present in the LazyChem dataset.

Scope: The mathematical 2^n value is only an upper bound. Symmetry and other stereogenic elements can change the number of distinct stereoisomers. A hypothetical configuration is not published as a compound record without a verified structure identity.

04India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNO EXACT MATCH FOUNDCAS 477-27-0 has no exact match in the reviewed published schedule.
SCOMETNO EXACT REVIEWED CAS MATCHCAS 477-27-0 has no exact match in the reviewed SCOMET list.
Review date2026-08-01Recheck the current official instruments for the material, concentration, activity and date in question.

05Names and relationships

Associated parent compound

Colchicin

View API and impurity family

Other names

  • Colchicine EP Impurity F
  • Colchiceine
  • 10-O-Demethylcolchicine
  • N-Acetyl trimethylcolchicinic acid
  • O-Demethylcolchicine
  • N-((S)-10-Hydroxy-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide
  • Colchicine BP Impurity F

Related records from the same parent family

06Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

07Sources