Chemical identity

Betamethasone Acetate EP Impurity A

CAS 378-44-9 · C22H29FO5

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-08089
PubChem CID9782
NameBetamethasone Acetate EP Impurity A
CAS RN378-44-9
Molecular formulaC22H29FO5
Molecular weight392.46
IUPAC name9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione
InChIKeyUREBDLICKHMUKA-DVTGEIKXSA-N

02Structure identifiers

2D structurePubChem CID 9782
Two-dimensional chemical structure of Betamethasone Acetate EP Impurity A, CAS 378-44-9
Two-dimensional structure for the PubChem identity linked to this record. Confirm the identifiers before analytical use.

The parsed structure contains 4 rings, includes aliphatic carbon, has 8 defined stereocentres, contains at least one halogen atom. These statements are calculated from the published structure string.

Defined stereocentres8
Unassigned stereocentres0
Ring count4
Secondary amines0
Tertiary amines0
N-methyl amine sites0
SMILESC[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C
InChINot listed
Formula from structureC22H29FO5
Molecular weight from structure392.46

03Stereochemistry

The published structure contains 8 defined and 0 unassigned tetrahedral stereocentres. The exact wedge and dash depiction is shown above.

Defined centres8Structure assigned
Unassigned centres0Structure unspecified
Assignment statusFully assignedExact published identity
Tetrahedral upper bound≤ 256Before symmetry reduction

Published same-connectivity configurations

2 records

These records have the same connectivity, molecular formula and protonation layer, but a different complete InChIKey stereochemical layer. Only separately structure-linked records are shown.

Scope: The mathematical 2^n value is only an upper bound. Symmetry and other stereogenic elements can change the number of distinct stereoisomers. A hypothetical configuration is not published as a compound record without a verified structure identity.

04India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNO EXACT MATCH FOUNDCAS 378-44-9 has no exact match in the reviewed published schedule.
SCOMETNO EXACT REVIEWED CAS MATCHCAS 378-44-9 has no exact match in the reviewed SCOMET list.
Review date2026-08-01Recheck the current official instruments for the material, concentration, activity and date in question.

05Names and relationships

Associated parent compound

Betamethasone; Dexamethasone

View API and impurity family

Other names

  • Dexamethasone EP Impurity B/ Betamethasone Dipropionate EP Impurity A/ Betamethasone Valerate EP Impurity A / Betamethasone Acetate EP Impurity A (Free Base)
  • Betamethasone(9-Fluoro-11b,17,21-Trihydroxy-16b-Methylpregna-1,4-Diene-3,20-Dione)
  • Dexamethasone EP Impurity B
  • (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
  • 9-alpha-Fluoro-16-beta-methylprednisolone
  • Betamethasone Dipropionate EP Impurity A
  • Betamethasone Valerate EP Impurity A
  • Betamethasone Acetate EP Impurity A

Related records from the same parent family

06Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

07Sources