Chemical identity

Azilsaratan Impurity E

CAS 136285-69-3 · C23H21N3O2

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-07397
PubChem CID15654655
NameAzilsaratan Impurity E
CAS RN136285-69-3
Molecular formulaC23H21N3O2
Molecular weight371.43
IUPAC name3-Amino-2-[[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]amino]benzoic Acid Ethyl Ester
InChIKeyQXQJYCWDJBDKKR-UHFFFAOYSA-N

02Structure identifiers

2D structurePubChem CID 15654655
Two-dimensional chemical structure of Azilsaratan Impurity E, CAS 136285-69-3
Two-dimensional structure for the PubChem identity linked to this record. Confirm the identifiers before analytical use.

The parsed structure contains 3 rings, includes aromatic atoms, includes aliphatic carbon. These statements are calculated from the published structure string.

Defined stereocentres0
Unassigned stereocentres0
Ring count3
Secondary amines1
Tertiary amines0
N-methyl amine sites0
SMILESCCOC(=O)C1=C(C(=CC=C1)N)NCC2=CC=C(C=C2)C3=CC=CC=C3C#N
InChINot listed
Formula from structureC23H21N3O2
Molecular weight from structure371.43

03Possible N-nitroso structures

Shown for structural screening only. These candidates are not confirmed impurities, formation predictions or analytical findings.

Matched amine site1 candidate
Chemical structure of Azilsaratan Impurity E with the matched amine site highlighted in amber
Amber identifies the screened atom and adjacent bonds.
Possible structure candidateUnverified identity
First calculated possible N-nitroso structure derived from Azilsaratan Impurity E, with the new N-nitroso group highlighted in amber
The new N-N=O atoms and bonds are highlighted. No CAS number or compound name is assigned by this calculation.
Candidate 1Possible N-nitroso structural candidate
Calculated formula
C23H20N4O3
Candidate SMILES
CCOC(=O)c1cccc(N)c1N(Cc1ccc(-c2ccccc2C#N)cc1)N=O

Interpretation: A structural alert alone does not establish that a nitrosamine forms. Evaluate nitrite sources, amine reagents, pH, temperature, process sequence, purge and analytical evidence.

04India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNO EXACT MATCH FOUNDCAS 136285-69-3 has no exact match in the reviewed published schedule.
SCOMETNO EXACT REVIEWED CAS MATCHCAS 136285-69-3 has no exact match in the reviewed SCOMET list.
Review date2026-08-01Recheck the current official instruments for the material, concentration, activity and date in question.

05Names and relationships

Associated parent compound

Azilsartan

View API and impurity family

Other names

  • Azilsartan Diaminophenyl Impurity
  • Azilsartan Impurity E
  • Ethyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoate
  • 136285-69-3
  • ethyl 3-amino-2-[[4-(2-cyanophenyl)phenyl]methylamino]benzoate
  • ETHYL-3-AMINO-2-[(2'-CYANOIPHENYL-4-YL) METHYL]-AMINO BENZOATE
  • MFCD09030635
  • ETHYL 3-AMINO-2-[(2'-CYANOBIPHENYL-4-YL)METHYL]AMINOBENZOATE
  • 3-Amino-2-[[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]amino]benzoic Acid Ethyl Ester
  • Azilsartan Impurity 9
  • A53V2J3N5T
  • SCHEMBL3982628

Related records from the same parent family

06Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

07Sources