Chemical identity

Apremilast EP Impurity D/ rac-4’-O-Desmethyl-4’-O-ethyl Apremilast

CAS 2448678-64-4 · C23H26N2O7S

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-06577
PubChem CID68439474
NameApremilast EP Impurity D/ rac-4’-O-Desmethyl-4’-O-ethyl Apremilast
CAS RN2448678-64-4
Molecular formulaC23H26N2O7S
Molecular weight474.53 g/mol
IUPAC nameN-(2-(1-(3,4-diethoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
InChIKeyQLVBUUCXCRRWIP-UHFFFAOYSA-N

02Structure identifiers

2D structurePubChem CID 68439474
Two-dimensional chemical structure of Apremilast EP Impurity D/ rac-4’-O-Desmethyl-4’-O-ethyl Apremilast, CAS 2448678-64-4
Two-dimensional structure for the PubChem identity linked to this record. Confirm the identifiers before analytical use.

The parsed structure contains 3 rings, includes aromatic atoms, includes aliphatic carbon. These statements are calculated from the published structure string.

Defined stereocentres0
Unassigned stereocentres1
Ring count3
Secondary amines0
Tertiary amines0
N-methyl amine sites0
SMILESCCOC1=C(C=C(C=C1)C(CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OCC
InChINot listed
Formula from structureC23H26N2O7S
Molecular weight from structure474.53 g/mol

03Stereochemistry

The published structure contains 0 defined and 1 unassigned tetrahedral stereocentre. The exact wedge and dash depiction is shown above.

Defined centres0Structure assigned
Unassigned centres1Structure unspecified
Assignment statusUnassignedExact published identity
Tetrahedral upper bound≤ 2Before symmetry reduction

Published same-connectivity configurations

1 record

These records have the same connectivity, molecular formula and protonation layer, but a different complete InChIKey stereochemical layer. Only separately structure-linked records are shown.

No additional structure-linked configuration with the same connectivity is currently present in the LazyChem dataset.

Scope: The mathematical 2^n value is only an upper bound. Symmetry and other stereogenic elements can change the number of distinct stereoisomers. A hypothetical configuration is not published as a compound record without a verified structure identity.

04India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNO EXACT MATCH FOUNDCAS 2448678-64-4 has no exact match in the reviewed published schedule.
SCOMETNO EXACT REVIEWED CAS MATCHCAS 2448678-64-4 has no exact match in the reviewed SCOMET list.
Review date2026-08-01Recheck the current official instruments for the material, concentration, activity and date in question.

05Names and relationships

Associated parent compound

Apremilast

View API and impurity family

Other names

  • Apremilast EP Impurity D
  • rac-4’-O-Desmethyl-4’-O-ethyl Apremilast
  • N-(2-(1-(3,4-diethoxyphenyl)-2-(Methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetaMide
  • 2448678-64-4
  • rac-4'-O-Desmethyl-4'-O-ethyl Apremilast
  • Apremilast Impurity 133
  • T9T65A4FKJ
  • SCHEMBL2915105
  • CS-0010081
  • Acetamide, N-[2-[1-(3,4-diethoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
  • N-[2-[1-(3,4-Diethoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide

Related records from the same parent family

06Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

07Sources