Chemical identity

Alfuzosin EP Impurity D / Alfuzosin Related Compound D / Alfuzosin Aminopropyl Impurity (Dihydrochloride Salt)

CAS 2732347-83-8 · C14H23Cl2N5O2

01Identity

Identifiers and names for this exact compound. Empty fields are left unassigned.

Lazychem IDLC-05397
PubChem CID129318752
NameAlfuzosin EP Impurity D / Alfuzosin Related Compound D / Alfuzosin Aminopropyl Impurity (Dihydrochloride Salt)
CAS RN2732347-83-8
Molecular formulaC14H23Cl2N5O2
Molecular weight364.27 g/mol
IUPAC nameN-(4-Amino-6,7-dimethoxyquinazolin-2-yl)-N-methylpropane-1,3-diamine Dihydrochloride
InChIKeyPPXDWABQZHJZLL-UHFFFAOYSA-N

02Structure identifiers

2D structurePubChem CID 129318752
Two-dimensional chemical structure of Alfuzosin EP Impurity D / Alfuzosin Related Compound D / Alfuzosin Aminopropyl Impurity (Dihydrochloride Salt), CAS 2732347-83-8
Two-dimensional structure for the PubChem identity linked to this record. Confirm the identifiers before analytical use.

The parsed structure contains 2 rings, includes aromatic atoms, includes aliphatic carbon, contains at least one halogen atom. These statements are calculated from the published structure string.

Defined stereocentres0
Unassigned stereocentres0
Ring count2
Secondary amines0
Tertiary amines1
N-methyl amine sites1
SMILESCN(CCCN)C1=NC2=CC(=C(C=C2C(=N1)N)OC)OC.Cl.Cl
InChINot listed
Formula from structureC14H23Cl2N5O2
Molecular weight from structure364.27 g/mol

03Possible N-nitroso structures

Shown for structural screening only. These candidates are not confirmed impurities, formation predictions or analytical findings.

Matched amine site1 candidate
Chemical structure of Alfuzosin EP Impurity D / Alfuzosin Related Compound D / Alfuzosin Aminopropyl Impurity (Dihydrochloride Salt) with the matched amine site highlighted in amber
Amber identifies the screened atom and adjacent bonds.
Possible structure candidateUnverified identity
First calculated possible N-nitroso structure derived from Alfuzosin EP Impurity D / Alfuzosin Related Compound D / Alfuzosin Aminopropyl Impurity (Dihydrochloride Salt), with the new N-nitroso group highlighted in amber
The new N-N=O atoms and bonds are highlighted. No CAS number or compound name is assigned by this calculation.
Candidate 1Possible N-nitroso structural candidate
Calculated formula
C13H20Cl2N6O3
Candidate SMILES
COc1cc2nc(N(CCCN)N=O)nc(N)c2cc1OC.Cl.Cl

Interpretation: A structural alert alone does not establish that a nitrosamine forms. Evaluate nitrite sources, amine reagents, pH, temperature, process sequence, purge and analytical evidence.

04India status for this compound

These results apply only to this exact compound name and CAS number. Confirm the current official instruments before making a regulatory decision.

NDPS / RCSNO EXACT MATCH FOUNDCAS 2732347-83-8 has no exact match in the reviewed published schedule.
SCOMETNO EXACT REVIEWED CAS MATCHCAS 2732347-83-8 has no exact match in the reviewed SCOMET list.
Review date2026-08-01Recheck the current official instruments for the material, concentration, activity and date in question.

05Names and relationships

Associated parent compound

Alfuzosin

View API and impurity family

Other names

  • Alfuzosin EP Impurity D (Dihydrochloride Salt)
  • N2-(3-Aminopropyl)-6, 7-dimethoxy-N2-methylquinazoline-2, 4-diamine dihydrochloride
  • Alfuzosin Aminopropyl Impurity
  • Alfuzosin Related Compound D
  • N-(4-Amino-6,7-dimethoxyquinazolin-2-yl)-N-methylpropane-1,3-diamine Dihydrochloride
  • 2732347-83-8

Related records from the same parent family

06Documented history

Dated discovery, occurrence, use and issue claims are published only when a suitable primary or government source is available.

No dated history available

No verified discovery, first report, occurrence, use or issue event is currently available for this identity.

07Sources